Sun B Som® is a Liposomal Amphotericin B (50 mg) injectable product produced in lyophilized (freeze-dried) form for intravenous administration. This medication belongs to the class of potent systemic antifungals and is specifically used to treat severe, invasive, and life-threatening fungal infections. The liposomal formulation of Sun B Som increases efficacy and reduces renal (kidney) toxicity compared to conventional Amphotericin B. This drug is administered exclusively in hospital settings under the supervision of an infectious disease specialist.
Amphotericin B binds to ergosterol in the fungal cell wall, creating pores that cause the leakage of cellular components, leading to fungal death. The liposomal form of Sun B Som encapsulates the drug within liposomal nanoparticles, which results in:
Reduced damage to sensitive tissues such as the kidneys.
Effective concentration at the site of infection.
Increased patient tolerance.
Reduced need for high doses and shorter treatment cycles.
This formulation is one of the most advanced and safest types of Amphotericin B.
Store in the refrigerator at temperatures between 2°C to 8°C.
Do not freeze the medication.
Keep in the original box to protect from light.
Inspect the vial for discoloration or damage before use.
Preparation and administration must only be performed by authorized healthcare personnel.
Prohibited for use without the supervision of a specialist physician.
Use with caution in patients with pre-existing renal problems.
Potential for fever, chills, hypotension (low blood pressure), and allergic reactions during infusion.
Use during pregnancy only if it is a vital necessity.
Use with caution and under medical supervision during lactation.
Monitoring blood and kidney function tests during treatment is mandatory.
Contraindications:
Severe hypersensitivity to Amphotericin B or liposomal components.
Concurrent use of highly nephrotoxic drugs (requires extreme caution).
Injection outside of a hospital environment or without resuscitation equipment.
Common Side Effects: Fever and chills during infusion, chest pain, nausea and vomiting, headache, and infusion-related reactions.
Potential Side Effects: Renal impairment (less common than with the conventional type), hypokalemia (low potassium), hypomagnesemia (low magnesium), pain at the injection site, hypotension or tachycardia.
Anemia may occur during long-term treatment.
Monitoring patient symptoms during infusion is critical.
Sun B Som is supplied in a durable and standard box containing one lyophilized vial of 50 mg Liposomal Amphotericin B. The packaging is designed to protect the vial from impact, moisture, and contamination. Complete information, including product name, dosage, administration method, storage conditions, batch number, and expiration date, is printed legibly on the box. This product is designed for hospital use only, and its packaging quality complies with pharmaceutical safety standards.
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